Career Opportunities
Aduro is a dynamic, fast-paced company on the cutting edge of immunotherapy. We are seeking talented, devoted and team-oriented employees. Aduro is an equal-opportunity employer and offers a competitive benefits package.

Please view the current opportunities below. To apply, please send a pdf of your resume to: careers@adurobiotech.com

Thank you for your interest in Aduro.


CURRENT OPENINGS

Immune Monitoring & Biomarker Development, Senior Scientist

Job Description:
The successful candidate will lead immune monitoring and biomarker development in support of Aduro’s clinical and translational programs.   The candidate will be involved in designing, executing and analyzing experiments to establish immune monitoring and biomarker assays with the focus on predictive and/or pharmacodynamics biomarker development.  The candidate will lead the testing of specimens collected from previous and ongoing clinical and translational studies.   The position will provide the unique opportunity to characterize and identify immune biomarkers that correlate with clinical outcome.  The person will be responsible for conducting studies as well as interacting with other groups within the department or with external collaborators.
 
Primary Responsibilities:
  • Provide scientific leadership within research and development and drive the establishment and testing of biomarkers
  • Establish and qualify various immunological and biomarker assays, such as cytokine flow cytometry, ELISPOT, and ELISA for immune monitoring and biomarker testing in humans
  • Participate in the development and implementation of studies supporting the development of Aduro’s immunotherapies
  • Lead clinical biomarker and immune monitoring activities in support of ongoing clinical programs
  • Establish and actively manage academic collaborations
  • Establish and actively manage activities at contracting laboratories as required
  • Record, analyze, and report results
Requirements:
  • Ph.D. in Immunology or Cell Biology
  • Minimum of 6-8 years post-doctoral research experience in a research and/or development environment and a record of outstanding research
  • Proven experience developing assays supporting biological products for human use, within a pharmaceutical or biotechnology firm
  • Extensive knowledge in human T cell biology and in related disease models for cancer and/or infectious disease
  • Comprehensive knowledge in immunology, cell biology and related methodologies such as WB, ELISA and FACS
  • Hands-on experience with cellular immune assays and general cell cultures techniques involving cell lines as well as primary cells
  • Experience with molecular biology techniques is advantageous
  • Excellent problem solving skills, applying scientific methods to resolution
  • Ability to work independently
  • Goal-oriented; ability to see the whole picture yet remain detail oriented
  • Excellent communication and presentation skills (written, verbal, interpersonal, listening)
  • Ability to understand and adhere to time-lines, schedules, task prioritization
  • Flexible; ability to adapt to changing priorities
  • Team oriented
  • Experience working with a contract development organization is a plus
  • Experience managing non-Ph.D. scientists preferred
 


Accounting Manager/Senior Manager

Job Description:
Ensure that the company’s financial statements are of the highest standards of quality, GAAP compliant and useful to management and the investing public. Perform accounting operations functions, including preparation of monthly journal entries and account reconciliations, oversight of the stock administration process and equity compensation expense, and monitoring the accuracy and efficiency of financial statement close process.
 
Primary Responsibilities:
  • Prepare monthly, quarterly and annual financial statements in accordance with GAAP
  • Prepare and review monthly journal entries and account reconciliations
  • Assist with accounting software system implementation as primary administrator
  • Analyze and interpret financial information and recommend system improvements
  • Cash management activities, such as account balance monitoring and bank reconciliations
  • Prepare budget vs. actual financial reports for management
  • Develop and maintain internal controls for key processes ensuring all financial reporting controls are operating effectively
  • Implement and update accounting policies and procedures to respond to changes in the Company’s business, SEC/GAAP regulations, and preparation for SOX 404 requirements
  • Research accounting literature and apply technical standards in the areas of clinical and R&D accruals, stock compensation and revenue recognition
  • Prepare accounting and financial reporting position papers on an as-needed basis for review by management
  • Perform equity compensation calculations in accordance with FAS123R for stock options granted to employees and consultants, warrants and oversee recordkeeping
  • Prepare and provide auditors and tax consultants with accounting information on a timely basis for financial statement audits, income tax provisions and tax returns
  • Assist with future SEC filings (Edgar and XBRL) including but not limited to S-1 and 10-K
 Requirements:
  •  BA/BS in business, accounting or related field
  • Experience with a Big Four public accounting firm is highly preferred/Active CPA
  • 5-years of increasingly responsible accounting and reporting experience; SOX 404 implementation and compliance experience a plus
  • Experience with Quickbooks, MS Dynamics/Great Plains, CapMx/Solium desired
  • High level of attention to detail, aptitude for planning/managing deadlines
  • Ability to maintain confidentiality over all finance and accounting matters
  • Exceptional communication and presentation skills
  • Creative approach to problem solving
  • Ability to self-motivate and function independently, driven towards superior effort and performance
  • Flexible with a strong ability to work in a dynamic environment within a team approach
  • Biotech industry experience highly preferred


Clinical Trial Manager

Job Description:
This is a full-time, permanent position for a Clinical Trial Manager (CTM) that provides comprehensive oversight of clinical trials in a small biotechnology company.  The position requires an individual with clinical trial management experience, who has strong, professional written and verbal communication skills, good organization and attention to detail, and the ability to consistently provide high-quality work while prioritizing tasks and meeting timelines.  This person must be interested in working in a fast-paced, team-oriented environment and be adaptable to rapidly changing priorities.
 
Primary Responsibilities:
  • Manages all operational activities pertaining to the execution of early-phase clinical trials, including day-to-day interactions with CROs, vendors, consultants and clinical sites as necessary
  • Provides leadership to the clinical study team to ensure efficient and effective trial conduct
  • In conjunction with Management, develops study timelines and budgets
  • Maintains systems for tracking study progress in order to provide timely updates to Management; monitors study progress to ensure adherence to timelines and continued compliance to SOPs and applicable regulations
  • Identifies tasks required for successful study execution and directs team members (including CROs and vendors) to effectively accomplish objectives
  • Coordinates the development of study documents including Study Reference Manuals, Pharmacy Binders and CRFs
  • Prepares, collects and tracks required regulatory documentation from clinical sites
  • Manages the monitoring of clinical studies, including development of monitoring plans and supervision of site monitors and site communications; may include some site monitoring and/or co-monitoring
  • Reviews monitoring reports, tracks study invoices (sites and vendors) and maintains study files
  • Coordinates the evaluation and selection of new investigators and vendors such as central laboratory services and CROs
  • Directs the planning of site initiation visits, Investigator Meetings and other study meetings (e.g., Data Monitoring Committee)
  • Works with Medical Monitor to manage critical safety issues
  • Manages high-level study issues that require cross-functional and/or Management input
  • Coordinates development of database specifications, edit specifications and Case Report Forms for electronic data capture (EDC) or paper-based data management systems
  • Projects, orders and tracks clinical investigational drug and non-drug study supplies
  • May manage CRAs and contract research staff, including providing mentoring opportunities and development plans for direct reports
  • Contributes to development and maintenance of Clinical department operations, including review/create SOPs
 
Requirements/Qualifications/Skills:
  • Bachelor’s degree with a minimum of 5 years’ industry experience, with at least 3 years in direct clinical trial management (or equivalent combination of education and experience)
  • Knowledgeable in current Good Clinical Practice requirements and their application to the conduct of clinical studies in the United States
  • Experience with early-phase, oncology, immunology and/or ex-US clinical studies a plus
  • Strong communication (verbal, written, listening) and interpersonal skills with ability to communicate effectively across different levels of the organization
  • Proficient in Microsoft Word, Excel and PowerPoint; MS Project also preferred
  • Ability to work independently and manage time appropriately (timelines, schedules, task prioritization)
  • Well-organized with attention to detail and accuracy
  • Travel may be required up to 25% in both the U.S. and abroad
 


Scientist, Immunology/Cell Biology STING Program

Summary & Scope:
We are seeking a dedicated, energetic and creative scientist who will contribute to the development of First-in-Human (FIH) clinical candidates utilizing proprietary small molecules (cyclic dinucleotides, or CDNs) that activate the STING (Stimulator of Interferon Genes) signaling pathway. These molecules can be applied broadly in various cancer immunotherapy, infectious disease and autoimmune/inflammatory settings. The ideal candidate will possess a diverse scientific knowledge and have excellent laboratory skills in the areas of molecular biology, biochemistry, immunology and animal models of cancer and/or infectious disease. The primary focus of this position will be to work with the pre-clinical project team to conduct critical path activities necessary to advance a CDN-based FIH investigational agent to human trials.   
 
Primary Responsibilities:
  • Contribute to the research and development of FIH product candidates utilizing proprietary CDN-based STING-activating small molecules. 
  • Develop and execute in vitro cell based and biochemical assays, as well as in vivo experiments to evaluate the potency and mechanism of action of novel CDNs and formulations.
  • Work with research and development groups in the design and implementation of safety, characterization, and stability assays to support clinical development of CDNs.
  • Evaluate, interpret and report scientific results and present work internally and at scientific meetings. 
  • Contribute to writing of competitive grant proposals, regulatory documents, patent applications and scientific publications.
  • Initiate and/or maintain relationships with contract research laboratories and academic collaborators.
  • Foster strategic external collaborations with thought leaders.
 
Requirements:
  • Ph.D. in Immunology, Cell Biology, Biochemistry or Molecular Biology or a related discipline.
  • A minimum 2 – 5 years post-doctoral or relevant industrial experience in preclinical research and development.
  • Sound scientific knowledge of innate and acquired immunity.
  • Extensive expertise with cellular and biochemical assays.
  • Experience analyzing T cell, B cell, and dendritic cell responses, and familiarity with techniques including flow cytometry, ELISA, ICS, ELISPOT assays, etc.
  • Expertise with primary human immune cells preferred.
  • Familiarity with adjuvant formulations and safety assays a plus.
  • Understanding of and experience with the drug development process, particularly for vaccines and/or other protein drugs.
  • Good organization and excellent problem solving skills with the ability to adhere to tight timelines.
  • Excellent interpersonal and communication skills (oral and written).
  • Willingness to adapt to changing priorities.
  • Ability to work independently as well as contribute actively to an integrated team.
  • The successful candidate must possess a significant publication and/or intellectual property record.


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